Illumina 850K Methylation Microarray DNA Methylation Sequencing CapitalBiotech

Widely Used: Our methylation technology platform is the most cited in scientific literature. It has been utilized to detect methylation in 10,181 samples by the Cancer Genome Atlas (TCGA) program in the United States and 9,246 samples by the International Cancer Genome Consortium (ICGC).

High Cost-Effectiveness: Our platform can analyze over 850,000 methylation sites with single-base resolution, allowing for the precise detection of methylation locations.

High Repeatability: Our DNA methylation analysis technology boasts a technical repeatability correlation (R²) greater than 0.98. Additionally, the correlation (R²) between the 450K intersection probe (850K vs. 450K) is also greater than 0.98.

Experienced: We have years of experience in providing DNA methylation chip services. Our project research areas include tumors, cardiovascular diseases, mental illnesses, immune diseases, drug epigenomes, reproduction and development, stem cells, and traditional Chinese medicine constitution.

Characteristic Analysis: Our data analysis team has extensive experience and has independently developed a illumina 850k methylation array chip analysis process. We offer tailored data analysis plans based on your experimental design. We also correct for cellular components to eliminate the interference of cellular heterogeneity, ensuring more rigorous and reliable results.

1. DNA Extraction 2. QUBIT Quantification 3. Hydrosulphite conversion 4. Whole Genome Methylation amplification 5. 850k methylation array chip hybridization, elution extension and scanning  6. DNA methylation data analysis

Illumina 850k methylation array testing result

Illumina 850k Mmethylation Array Application cases:

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

Genome-wide analysis of DNA methylation and acute coronary syndrome