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Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit CapitalBio

Introduction of Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit

Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) is an accurate detection method that combines the advantages of ultra-high multiplex target amplification and high-throughput sequencing technology. By extracting and enriching nucleic acids from sputum and bronchoalveolar lavage fluid, using the sequencing platform to sequence the pathogen's genes, and comparing and analyzing sequence information against a database, this kit can identify 183 types of respiratory system infection pathogens such as DNA/RNA viruses, bacteria, fungi, and mycoplasma, as well as 34 types of drug-resistant genes/mutation sites, assisting in precise clinical diagnosis.


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Features of Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit

(1) High sensitivity: The LOD can be as low as 10 copies/ml;

(2) Quick test: The turnaround time can be as fast as 16 h;

(3) Broad coverage: 95% of clinically prevalent pathogens are covered;

(4) Precision treatment: 30 drug-resistant genes related to 6 major classes of antibiotics are detected, assisting clinicians in formulating precise diagnosis and treatment plans.


Applicable Populations and Scenarios of Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit

It is used for the detection of common pathogens in adult and pediatric patients with community - acquired pneumonia or hospital - acquired pneumonia, upper/lower respiratory tract infections in immunocompromised individuals, and other non - critical, non - emergency, non - severe, and non - difficult respiratory infection patients.

Order Information of Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit

Cat. No

Product Name

Packaging Specification

CBT3DO3TLB

Pathogen Targeted Next Generation Sequencing (tNGS) Kit

192 tests/kit


Background Information of Respiratory System Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit

Respiratory tract infection (RTI) is the most common type of infection responsible for pandemics. Furthermore, pathogens that cause RTI are diverse. Mixed viral and bacterial infections can lead to more severe clinical manifestations. Traditional methods of testing for respiratory pathogens have the disadvantages of long TAT, low sensitivity, and difficulty in identifying co-infections by more than one pathogen. tNGS has higher efficiency in the accurate detection of respiratory pathogens, including identifying multiple pathogens in cases of mixed infection. Furthermore, tNGS shows higher detection rate than traditional culture-based approach and a similar detection rate with mNGS.


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