The Disease Susceptibility Genetic Test-APOE CapitalBio

Features of the Disease Susceptibility Genetic Test-APOE

Among lipid-lowering drugs, statins are the most important, with over 60% of patients will use statins to control blood lipids. Statins are hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors and are widely used for the prevention and treatment of cardiovascular disease due to their cholesterol-lowering properties. Most patients with coronary heart disease may require lifelong statin therapy.

Studies have reported that statins exhibtis the greatest lipid-lowering efficacy in APOE 2 carriers, while their efficacy is diminished in  APOE 4 carriers. Detection of APOE gene before taking statins can scientifically evaluate the effect of individual medication and help patients in personalized drug selection.

1. People with bad eating habits, such as: like eating high-fat, high-calorie, pickled, smoked, fried foods.

2. People who smoke, who have been exposed to secondhand smoke for a long time, and who drink excessively.

3. People with irregular life and rest, long-term insomnia or staying up late, and lack of exercise.

4. People with long-term mental stress, anxiety, tension, irritability.

5. Overweight, obese people.

6. People with family history of cardiovascular and cerebrovascular diseases.

7. People with dyslipidemia.

The test is based on biochip technology. By detecting two gene loci that determine APOE protein polymorphism, it evaluates its impact on the risk of cardiovascular and cerebrovascular diseases, metabolic diseases, etc., and guides the subjects to carry out effective prevention and treatment, including adjusting diet, improving lifestyle, appropriate use of drugs, strengthening physical examination, etc.

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