Transcriptome can change with the external environment, which is different from the genome. Since the transcriptome includes the transcription of all mRNA in cells, except for abnormal mRNA degradation (like transcriptional decay), the transcriptome reflects the genes that are actively expressed at any given time.
Transcriptome research is the basis and starting point of gene function and structure research. Through NGS technology, we can comprehensively obtain the information expressed by mRNA of a specific tissue or organ in a certain state.
Long non-coding RNA (lncRNA) is a kind of non-coding protein RNA with a length of more than 200nt. It regulates gene expression by binding with DNA, RNA, or protein.