Genitourinary Tract Infection Pathogen Targeted Next-generation Sequencing (tNGS) Kit CapitalBio

Features

(1)Non-invasive: Urine can be used as the sample.

(2) Quick test: The turnaround time can be as fast as 13.5 h;

(3) High sensitivity: The LOD is as low as 10-300 copies/ml;

(4) Comprehensive detection: Covering 34 types of genitourinary tract infection pathogens, and 38 types of HPVs, enabling effective detection of co-infection.

Applicable Populations and Scenarios

• Patients with mixed, complex, refractory genitourinary tract infections, or those with infections of unknown etiology;

• Population preparing for pregnancy, with infertility, or those with a history of adverse pregnancy;

• Cervical cancer screening, or patients with a history of HPV infection;

• Gynecological screening before gynecological surgery or embryo transfer

• Special population with multiple sexual partners without protective measures

• Patients with suspected condyloma acuminatum.

Order Information

Background Information

Urinary tract infections (UTIs) rank among the most prevalent bacterial infections worldwide, affecting approximately 100 million individuals annually. Urine culture has been the gold standard for UTI diagnosis traditionally. However, this method typically takes 24–48 h to obtain results, and an additional 24 h for antimicrobial susceptibility testing, causing delays in treatment. Moreover, urine culture shows low sensitivity for fastidious or slow-growing organisms, often fail to detect polymicrobial infections accurately, and may miss difficult-to-culture or uncultivable bacteria. These advantages may result in misdiagnosis, inappropriate antibiotic use, or potentially worse clinical outcomes.

Targeted Next-Generation Sequencing (tNGS) has recently emerged as a promising diagnostic tool for infectious diseases, offering several advantages over traditional methods: the results are obtained rapidly, typically within hours; a broad range of pathogens, including fastidious and unculturable organisms, can be detected; polymicrobial infections can be detected with high sensitivity. quantitative detection and antimicrobial resistance information can be provided, etc.